I always look at a few things..
1) Run in. As long we are in the mix at this point, do we an easier run in than our main rival? I'd say it was even.
2) Xmas. During the period of intense games, do we have easy fixtures with good rest in between? Yes and No. And do we have home fixtures without much travel? Not this yes. But compared to City, we have easier fixtures over this period.
3) The Start. Do we have a chance to build momentum and possibly check off some hard games when teams aren't full acclimatised to the league. I think we do.
4) Any difficult cluster of games or ones around CL times. There's possibly a difficult cluster from Feb 6th (City) to April 3rd (Arsenal). None of those teams are mugs save Fulham. Usually around the last 16 / quarter final ties.
5) When we play City - Home and Away. Last couple of years, we've played them at Anfield first. This year, it's the opposite. Vice-versa with United. We should have a chance to build a little momentum before we play them. Although the game after them both times is Leicester. Hopefully we don't carry any bookings going into that one.
6) Avoid Chelsea away in May? Check.